Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome

Artemisinin and its derivatives (collectively referred to as ARTs) rapidly reduce the parasite burden in Plasmodium falciparum infections, and antimalarial control is highly dependent on ART combination therapies (ACTs). Decreased sensitivity to ARTs is emerging, making it critically important to un...

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Detalles Bibliográficos
Autores principales: Bridgford, Jessica L., Xie, Stanley C., Cobbold, Simon A., Pasaje, Charisse Flerida A., Herrmann, Susann, Yang, Tuo, Gillett, David L., Dick, Lawrence R., Ralph, Stuart A., Dogovski, Con, Spillman, Natalie J., Tilley, Leann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143634/
https://www.ncbi.nlm.nih.gov/pubmed/30228310
http://dx.doi.org/10.1038/s41467-018-06221-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143634/
https://www.ncbi.nlm.nih.gov/pubmed/30228310
http://dx.doi.org/10.1038/s41467-018-06221-1

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