IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction

Background: Elevated interleukin-6 (IL-6) and complement activation are associated with detrimental effects of inflammation in coronary artery disease (CAD). The complement anaphylatoxins C5a and C3a interact with their receptors; the highly inflammatory C5aR1, and the C5aR2 and C3aR. We evaluated t...

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Detalles Bibliográficos
Autores principales: Orrem, Hilde L., Nilsson, Per H., Pischke, Søren E., Kleveland, Ola, Yndestad, Arne, Ekholt, Karin, Damås, Jan K., Espevik, Terje, Bendz, Bjørn, Halvorsen, Bente, Gregersen, Ida, Wiseth, Rune, Andersen, Geir Ø., Ueland, Thor, Gullestad, Lars, Aukrust, Pål, Barratt-Due, Andreas, Mollnes, Tom E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143659/
https://www.ncbi.nlm.nih.gov/pubmed/30258440
http://dx.doi.org/10.3389/fimmu.2018.02035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143659/
https://www.ncbi.nlm.nih.gov/pubmed/30258440
http://dx.doi.org/10.3389/fimmu.2018.02035

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