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ICAM-1-LFA-1 Dependent CD8+ T-Lymphocyte Aggregation in Tumor Tissue Prevents Recirculation to Draining Lymph Nodes

The quantity of T-lymphocytes reaching the draining lymph nodes from tumors is likely important to mount effective distant responses and for the establishment of long term systemic memory. Looking into mechanisms behind lymphocyte egress, we directed our attention to leukocyte adhesion mechanisms in...

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Detalles Bibliográficos
Autores principales: Yanguas, Alba, Garasa, Saray, Teijeira, Álvaro, Aubá, Cristina, Melero, Ignacio, Rouzaut, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143661/
https://www.ncbi.nlm.nih.gov/pubmed/30258446
http://dx.doi.org/10.3389/fimmu.2018.02084