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Carbamylated Erythropoietin Decreased Proliferation and Neurogenesis in the Subventricular Zone, but Not the Dentate Gyrus, After Irradiation to the Developing Rat Brain

Cranial radiotherapy for pediatric brain tumors causes progressive, debilitating late effects, including cognitive decline. Erythropoietin (EPO) has been shown to be neuroprotective and to promote neuroregeneration. Carbamylated erythropoietin (CEPO) retains the protective properties of EPO but is n...

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Detalles Bibliográficos
Autores principales: Osato, Kazuhiro, Sato, Yoshiaki, Osato, Akari, Sato, Machiko, Zhu, Changlian, Leist, Marcel, Kuhn, Hans G., Blomgren, Klas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143677/
https://www.ncbi.nlm.nih.gov/pubmed/30258396
http://dx.doi.org/10.3389/fneur.2018.00738