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Carbamylated Erythropoietin Decreased Proliferation and Neurogenesis in the Subventricular Zone, but Not the Dentate Gyrus, After Irradiation to the Developing Rat Brain
Cranial radiotherapy for pediatric brain tumors causes progressive, debilitating late effects, including cognitive decline. Erythropoietin (EPO) has been shown to be neuroprotective and to promote neuroregeneration. Carbamylated erythropoietin (CEPO) retains the protective properties of EPO but is n...
Autores principales: | Osato, Kazuhiro, Sato, Yoshiaki, Osato, Akari, Sato, Machiko, Zhu, Changlian, Leist, Marcel, Kuhn, Hans G., Blomgren, Klas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143677/ https://www.ncbi.nlm.nih.gov/pubmed/30258396 http://dx.doi.org/10.3389/fneur.2018.00738 |
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