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Modulation in the microRNA repertoire is responsible for the stage-specific effects of Akt suppression on murine neuroendocrine prostate cancer

Recent studies indicate a stage-specific, differential role for the oncogene Akt on various cancers. In prostate cancer (PCa), suppression of Akt activity in the advanced stages promoted transforming growth factor-β (TGFβ) pathway-mediated epithelial-to-mesenchymal transition (EMT) and metastasis to...

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Detalles Bibliográficos
Autores principales: Alwhaibi, Abdulrahman, Gao, Fei, Artham, Sandeep, Hsia, Bernard M., Mondal, Ashis, Kolhe, Ravindra, Somanath, Payaningal R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143703/
https://www.ncbi.nlm.nih.gov/pubmed/30238065
http://dx.doi.org/10.1016/j.heliyon.2018.e00796