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The Mitochondrial Ca(2+) Uniporter Complex (MCUC) of Trypanosoma brucei Is a Hetero-oligomer That Contains Novel Subunits Essential for Ca(2+) Uptake

The mitochondrial calcium uniporter complex (MCUC) is a highly selective channel that conducts calcium ions across the organelle inner membrane. We previously characterized Trypanosoma brucei’s MCU (TbMCU) as an essential component of the MCUC required for parasite viability and infectivity. In this...

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Detalles Bibliográficos
Autores principales: Huang, Guozhong, Docampo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143741/
https://www.ncbi.nlm.nih.gov/pubmed/30228243
http://dx.doi.org/10.1128/mBio.01700-18