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Structure–Function Relationships of Glycine and GABA(A) Receptors and Their Interplay With the Scaffolding Protein Gephyrin
Glycine and γ-aminobutyric acid (GABA) are the major determinants of inhibition in the central nervous system (CNS). These neurotransmitters target glycine and GABA(A) receptors, respectively, which both belong to the Cys-loop superfamily of pentameric ligand-gated ion channels (pLGICs). Interaction...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143783/ https://www.ncbi.nlm.nih.gov/pubmed/30258351 http://dx.doi.org/10.3389/fnmol.2018.00317 |