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Dickkopf-3 Causes Neuroprotection by Inducing Vascular Endothelial Growth Factor

Dickkopf-3 (Dkk3) is an atypical member of the Dkk family of Wnt inhibitors, which has been implicated in the pathophysiology of neurodegenerative disorders. However, the role of Dkk3 in mechanisms of cell degeneration and protection is unknown. We used Dkk3 knockout mice to examine how endogenous D...

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Detalles Bibliográficos
Autores principales: Busceti, Carla Letizia, Di Menna, Luisa, Bianchi, Franca, Mastroiacovo, Federica, Di Pietro, Paola, Traficante, Anna, Bozza, Giovanna, Niehrs, Christof, Battaglia, Giuseppe, Bruno, Valeria, Fornai, Francesco, Volpe, Massimo, Rubattu, Speranza, Nicoletti, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143799/
https://www.ncbi.nlm.nih.gov/pubmed/30258353
http://dx.doi.org/10.3389/fncel.2018.00292