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α-Synuclein and Noradrenergic Modulation of Immune Cells in Parkinson’s Disease Pathogenesis

α-synuclein (α-syn) pathology and loss of noradrenergic neurons in the locus coeruleus (LC) are among the most ubiquitous features of Parkinson’s disease (PD). While noradrenergic dysfunction is associated with non-motor symptoms of PD, preclinical research suggests that the loss of LC norepinephrin...

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Detalles Bibliográficos
Autores principales: Butkovich, Laura M., Houser, Madelyn C., Tansey, Malú G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143806/
https://www.ncbi.nlm.nih.gov/pubmed/30258347
http://dx.doi.org/10.3389/fnins.2018.00626