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In vitro-Induced Human IL-10(+) B Cells Do Not Show a Subset-Defining Marker Signature and Plastically Co-express IL-10 With Pro-Inflammatory Cytokines

Regulatory B cells (Breg) have been described as a specific immunological subsets in several mouse models. Identification of a human counterpart has remained troublesome, because unique plasma membrane markers or a defining transcription factor have not been identified. Consequently, human Bregs are...

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Detalles Bibliográficos
Autores principales: Lighaam, Laura C., Unger, Peter-Paul A., Vredevoogd, David W., Verhoeven, Dorit, Vermeulen, Ellen, Turksma, Annelies W., ten Brinke, Anja, Rispens, Theo, van Ham, S. Marieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143818/
https://www.ncbi.nlm.nih.gov/pubmed/30258433
http://dx.doi.org/10.3389/fimmu.2018.01913