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Aconitine-induced cardiac arrhythmia in human induced pluripotent stem cell-derived cardiomyocytes

Pre-clinical evaluation of cardiac dysfunction is important for assessing the safety of traditional or novel medicines due to the universality of potential drug-induced heart failure and irreversible arrhythmia. Aconitine (ACO), a traditionally used anti-pyretic, analgesic and anti-rheumatic drug, h...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Cai, Lin, Zhang, Jing, Qi, Xueyan, Lu, Chengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143858/
https://www.ncbi.nlm.nih.gov/pubmed/30233701
http://dx.doi.org/10.3892/etm.2018.6644