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Mixed lineage kinase-4 promotes gastric carcinoma tumorigenesis through suppression of the c-Jun N-terminal kinase signaling pathway

Mixed lineage kinase-4 (MLK-4) is an important member of the mixed-lineage family of kinases that regulates the extracellular signal-regulated kinases and c-Jun N-terminal kinase (JNK) signaling pathways. The functions and mechanisms of MLK-4 in cancer initiation and progression have not been well u...

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Detalles Bibliográficos
Autores principales: Xi, Yu, Niu, Jianhua, Li, Dongmei, He, Jiagen, Qin, Le, Peng, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143876/
https://www.ncbi.nlm.nih.gov/pubmed/30233678
http://dx.doi.org/10.3892/etm.2018.6618