Cargando…

Fibroblast growth factor receptor 1 antagonism attenuates lipopolysaccharide-induced activation of hepatic stellate cells via suppressing inflammation

Activated hepatic stellate cells (HSCs) serve key roles in hepatic fibrosis by producing excessive extracellular matrix (ECM) components. Lipopolysaccharide (LPS) has been found to be associated with hepatic fibrogenesis through direct interactions with HSCs. Recently, the fibroblast growth factor r...

Descripción completa

Detalles Bibliográficos
Autores principales: Lou, Dayong, Han, Jibo, Zhou, Liqin, Ma, Huanjie, Xv, Jianjiang, Shou, Junwei, Xu, Zhixiu, Jiang, Liqin, Qian, Yuanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143916/
https://www.ncbi.nlm.nih.gov/pubmed/30250515
http://dx.doi.org/10.3892/etm.2018.6586