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Adjunctive dexamethasone for the treatment of HIV-infected adults with tuberculous meningitis (ACT HIV): Study protocol for a randomised controlled trial

Background: Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Co-infection with HIV increases the risk of developing TBM, complicates treatment, and substantially worsens outcome. Whether corticosteroids confer a survival benefit in HIV-infected patients with TBM remains uncertai...

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Detalles Bibliográficos
Autores principales: Donovan, Joseph, Phu, Nguyen Hoan, Mai, Nguyen Thi Hoang, Dung, Le Tien, Imran, Darma, Burhan, Erlina, Ngoc, Lam Hong Bao, Bang, Nguyen Duc, Giang, Do Chau, Ha, Dang Thi Minh, Day, Jeremy, Thao, Le Thi Phuong, Thuong, Nguyen TT, Vien, Nguyen Nang, Geskus, Ronald B., Wolbers, Marcel, Hamers, Raph L, van Crevel, Reinout, Nursaya, Mugi, Maharani, Kartika, Hien, Tran Tinh, Baird, Kevin, Lan, Nguyen Huu, Kestelyn, Evelyne, Chau, Nguyen Van Vinh, Thwaites, Guy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143919/
https://www.ncbi.nlm.nih.gov/pubmed/30320225
http://dx.doi.org/10.12688/wellcomeopenres.14006.2