Antimicrobial peptide LL-37 and recombinant human mannose-binding lectin express distinct age- and pathogen-specific antimicrobial activity in human newborn cord blood in vitro

Background: There is a need to prevent and treat infection in newborns. One approach is administration of antimicrobial proteins and peptides (APPs) such as LL-37, a membrane-active cathelicidin antimicrobial peptide, and mannose-binding lectin (MBL), a pattern-recognition protein that binds to micr...

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Detalles Bibliográficos
Autores principales: Scheid, Annette, Li, Ning, Jeffers, Carleen, Borriello, Francesco, Joshi, Sweta, Ozonoff, Al, Pettengill, Matthew, Levy, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143923/
https://www.ncbi.nlm.nih.gov/pubmed/30271580
http://dx.doi.org/10.12688/f1000research.14736.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143923/
https://www.ncbi.nlm.nih.gov/pubmed/30271580
http://dx.doi.org/10.12688/f1000research.14736.1

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