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Presymptomatic white matter integrity loss in familial frontotemporal dementia in the GENFI cohort: A cross‐sectional diffusion tensor imaging study

OBJECTIVE: We aimed to investigate mutation‐specific white matter (WM) integrity changes in presymptomatic and symptomatic mutation carriers of the C9orf72,MAPT, and GRN mutations by use of diffusion‐weighted imaging within the Genetic Frontotemporal dementia Initiative (GENFI) study. METHODS: One h...

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Detalles Bibliográficos
Autores principales: Jiskoot, Lize C., Bocchetta, Martina, Nicholas, Jennifer M., Cash, David M., Thomas, David, Modat, Marc, Ourselin, Sebastien, Rombouts, Serge A.R.B., Dopper, Elise G.P., Meeter, Lieke H., Panman, Jessica L., van Minkelen, Rick, van der Ende, Emma L., Donker Kaat, Laura, Pijnenburg, Yolande A.L., Borroni, Barbara, Galimberti, Daniela, Masellis, Mario, Tartaglia, Maria Carmela, Rowe, James, Graff, Caroline, Tagliavini, Fabrizio, Frisoni, Giovanni B., Laforce, Robert, Finger, Elizabeth, de Mendonça, Alexandre, Sorbi, Sandro, Papma, Janne M., van Swieten, John C., Rohrer, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144447/
https://www.ncbi.nlm.nih.gov/pubmed/30250860
http://dx.doi.org/10.1002/acn3.601