ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability

Elevated N-methyl-D-aspartate receptor activity contributes to central sensitization. Our laboratories and others recently reported that disrupting protein–protein interactions downstream of N-methyl-D-aspartate receptors suppresses pain. Specifically, disrupting binding between the enzyme neuronal...

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Detalles Bibliográficos
Autores principales: Lee, Wan-Hung, Carey, Lawrence M, Li, Li-Li, Xu, Zhili, Lai, Yvonne Y, Courtney, Michael J, Hohmann, Andrea G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144507/
https://www.ncbi.nlm.nih.gov/pubmed/30157705
http://dx.doi.org/10.1177/1744806918801224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144507/
https://www.ncbi.nlm.nih.gov/pubmed/30157705
http://dx.doi.org/10.1177/1744806918801224

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