DNA binding with a minimal scaffold: structure–function analysis of Lig E DNA ligases

DNA ligases join breaks in the phosphodiester backbone of DNA by catalysing the formation of bonds between opposing 5′P and 3′OH ends in an adenylation-dependent manner. Catalysis is accompanied by reorientation of two core domains to provide access to the active site for cofactor utilization and en...

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Detalles Bibliográficos
Autores principales: Williamson, Adele, Grgic, Miriam, Leiros, Hanna-Kirsti S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144786/
https://www.ncbi.nlm.nih.gov/pubmed/30007325
http://dx.doi.org/10.1093/nar/gky622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144786/
https://www.ncbi.nlm.nih.gov/pubmed/30007325
http://dx.doi.org/10.1093/nar/gky622

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