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RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF

Given our previous demonstration that RBPJ binds a methylated repressor element and regulates smooth muscle cell (SMC)-specific gene expression, we used genome-wide approaches to identify RBPJ binding regions in human aortic SMC and to assess RBPJ’s effects on chromatin structure and gene expression...

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Detalles Bibliográficos
Autores principales: Rozenberg, Julian M, Taylor, Joan M, Mack, Christopher P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144787/
https://www.ncbi.nlm.nih.gov/pubmed/29931229
http://dx.doi.org/10.1093/nar/gky562