RBPJ binds to consensus and methylated cis elements within phased nucleosomes and controls gene expression in human aortic smooth muscle cells in cooperation with SRF

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Given our previous demonstration that RBPJ binds a methylated repressor element and regulates smooth muscle cell (SMC)-specific gene expression, we used genome-wide approaches to identify RBPJ binding regions in human aortic SMC and to assess RBPJ’s effects on chromatin structure and gene expression...

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Detalles Bibliográficos
Autores principales: Rozenberg, Julian M, Taylor, Joan M, Mack, Christopher P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144787/
https://www.ncbi.nlm.nih.gov/pubmed/29931229
http://dx.doi.org/10.1093/nar/gky562

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