In vitro selection of an XNA aptamer capable of small-molecule recognition

Despite advances in XNA evolution, the binding capabilities of artificial genetic polymers are currently limited to protein targets. Here, we describe the expansion of in vitro evolution techniques to enable selection of threose nucleic acid (TNA) aptamers to ochratoxin A (OTA). This research establ...

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Detalles Bibliográficos
Autores principales: Rangel, Alexandra E, Chen, Zhe, Ayele, Tewoderos M, Heemstra, Jennifer M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144807/
https://www.ncbi.nlm.nih.gov/pubmed/30085205
http://dx.doi.org/10.1093/nar/gky667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144807/
https://www.ncbi.nlm.nih.gov/pubmed/30085205
http://dx.doi.org/10.1093/nar/gky667

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