Characterizing the 3D structure and dynamics of chromosomes and proteins in a common contact matrix framework

Conformational ensembles of biopolymers, whether proteins or chromosomes, can be described using contact matrices. Principal component analysis (PCA) on the contact data has been used to interrogate both protein and chromosome structures and/or dynamics. However, as these fields have developed separ...

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Detalles Bibliográficos
Autores principales: Lindsay, Richard J, Pham, Bill, Shen, Tongye, McCord, Rachel Patton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144818/
https://www.ncbi.nlm.nih.gov/pubmed/29992238
http://dx.doi.org/10.1093/nar/gky604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144818/
https://www.ncbi.nlm.nih.gov/pubmed/29992238
http://dx.doi.org/10.1093/nar/gky604

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