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Argonaute-based programmable RNase as a tool for cleavage of highly-structured RNA

The recent identification and development of RNA-guided enzymes for programmable cleavage of target nucleic acids offers exciting possibilities for both therapeutic and biotechnological applications. However, critical challenges such as expensive guide RNAs and inability to predict the efficiency of...

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Detalles Bibliográficos
Autores principales: Dayeh, Daniel M, Cantara, William A, Kitzrow, Jonathan P, Musier-Forsyth, Karin, Nakanishi, Kotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144825/
https://www.ncbi.nlm.nih.gov/pubmed/29897478
http://dx.doi.org/10.1093/nar/gky496