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Shared nucleotide flanks confer transcriptional competency to bZip core motifs

Sequence-specific DNA binding recruits transcription factors (TFs) to the genome to regulate gene expression. Here, we perform high resolution mapping of CEBP proteins to determine how sequence dictates genomic occupancy. We demonstrate a fundamental difference between the sequence repertoire utiliz...

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Detalles Bibliográficos
Autores principales: Cohen, Daniel M, Lim, Hee-Woong, Won, Kyoung-Jae, Steger, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144830/
https://www.ncbi.nlm.nih.gov/pubmed/30085281
http://dx.doi.org/10.1093/nar/gky681