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Amphibian (Xenopus laevis) Interleukin-8 (CXCL8): A Perspective on the Evolutionary Divergence of Granulocyte Chemotaxis

The glutamic acid-leucine-arginine (ELR) motif is a hallmark feature shared by mammalian inflammatory CXC chemokines such the granulocyte chemo-attractant CXCL8 (interleukin-8, IL-8). By contrast, most teleost fish inflammatory chemokines lack this motif. Interestingly, the amphibian Xenopus laevis...

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Detalles Bibliográficos
Autores principales: Koubourli, Daphne V., Yaparla, Amulya, Popovic, Milan, Grayfer, Leon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145007/
https://www.ncbi.nlm.nih.gov/pubmed/30258441
http://dx.doi.org/10.3389/fimmu.2018.02058