Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles

BACKGROUND: Messenger RNA (mRNA) has gained remarkable attention as an alternative to DNA-based therapies in biomedical research. A variety of biodegradable nanoparticles (NPs) has been developed including lipid-based and polymer-based systems for mRNA delivery. However, both systems still lack in a...

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Detalles Bibliográficos
Autores principales: Yasar, Hanzey, Biehl, Alexander, De Rossi, Chiara, Koch, Marcus, Murgia, Xabi, Loretz, Brigitta, Lehr, Claus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145106/
https://www.ncbi.nlm.nih.gov/pubmed/30231888
http://dx.doi.org/10.1186/s12951-018-0401-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145106/
https://www.ncbi.nlm.nih.gov/pubmed/30231888
http://dx.doi.org/10.1186/s12951-018-0401-y

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