Cargando…

Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles

BACKGROUND: Messenger RNA (mRNA) has gained remarkable attention as an alternative to DNA-based therapies in biomedical research. A variety of biodegradable nanoparticles (NPs) has been developed including lipid-based and polymer-based systems for mRNA delivery. However, both systems still lack in a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yasar, Hanzey, Biehl, Alexander, De Rossi, Chiara, Koch, Marcus, Murgia, Xabi, Loretz, Brigitta, Lehr, Claus-Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145106/ https://www.ncbi.nlm.nih.gov/pubmed/30231888 http://dx.doi.org/10.1186/s12951-018-0401-y

Ejemplares similares

Lipid–Polymer Hybrid Nanoparticles for mRNA Delivery to Dendritic Cells: Impact of Lipid Composition on Performance in Different Media
por: Kliesch, Lena, et al.
Publicado: (2022)

Starch-Chitosan Polyplexes: A Versatile Carrier System for Anti-Infectives and Gene Delivery
por: Yasar, Hanzey, et al.
Publicado: (2018)

Itaconic Acid Increases the Efficacy of Tobramycin against Pseudomonas aeruginosa Biofilms
por: Ho, Duy-Khiet, et al.
Publicado: (2020)

Co-Delivery of mRNA and pDNA Using Thermally Stabilized Coacervate-Based Core-Shell Nanosystems
por: Nasr, Sarah S., et al.
Publicado: (2021)

Synthesis and Biopharmaceutical Characterization of Amphiphilic Squalenyl Derivative Based Versatile Drug Delivery Platform
por: Ho, Duy-Khiet, et al.
Publicado: (2020)

Drug delivery for fighting infectious diseases: a global perspective
por: Loretz, Brigitta, et al.
Publicado: (2021)

Tofacitinib Loaded Squalenyl Nanoparticles for Targeted Follicular Delivery in Inflammatory Skin Diseases
por: Christmann, Rebekka, et al.
Publicado: (2020)

Squalenyl Hydrogen Sulfate Nanoparticles for Simultaneous Delivery of Tobramycin and an Alkylquinolone Quorum Sensing Inhibitor Enable the Eradication of P. aeruginosa Biofilm Infections
por: Ho, Duy‐Khiet, et al.
Publicado: (2020)

Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis
por: Haque, A. K. M. Ashiqul, et al.
Publicado: (2018)

Spray-dried lactose-leucine microparticles for pulmonary delivery of antimycobacterial nanopharmaceuticals
por: Thiyagarajan, Durairaj, et al.
Publicado: (2021)

Leaky gut model of the human intestinal mucosa for testing siRNA-based nanomedicine targeting JAK1
por: Hartwig, Olga, et al.
Publicado: (2022)

Evaluation of Cell Proliferation and Wound Healing Effects of Vitamin A Palmitate-Loaded PLGA/Chitosan-Coated PLGA Nanoparticles: Preparation, Characterization, Release, and Release Kinetics
por: Baghirova, Lala, et al.
Publicado: (2023)

In-vitro Transcribed mRNA Delivery Using PLGA/PEI Nanoparticles into Human Monocyte-derived Dendritic Cells
por: Sharifnia, Zarin, et al.
Publicado: (2019)

Chitosan Oleate Coated PLGA Nanoparticles as siRNA Drug Delivery System
por: Miele, Dalila, et al.
Publicado: (2021)

Human Skin Permeation Enhancement Using PLGA Nanoparticles Is Mediated by Local pH Changes
por: Luengo, Javiana, et al.
Publicado: (2021)

Intracellular Dynamics of Extracellular Vesicles by Segmented Trajectory Analysis
por: Rautaniemi, Kaisa, et al.
Publicado: (2022)

Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neurons
por: Heise, Christopher, et al.
Publicado: (2014)

Disrupting Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Latent Replication with a Small Molecule Inhibitor
por: Berwanger, Aylin, et al.
Publicado: (2023)

Direct measurements of mRNA translation kinetics in living cells
por: Metelev, Mikhail, et al.
Publicado: (2022)

Modelling ribosome kinetics and translational control on dynamic mRNA
por: Dykeman, Eric C.
Publicado: (2023)

Screening the Molecular Framework Underlying Local Dendritic mRNA Translation
por: Namjoshi, Sanjeev V., et al.
Publicado: (2017)

Antibiofilm Coatings Based on PLGA and Nanostructured Cefepime-Functionalized Magnetite
por: Ficai, Denisa, et al.
Publicado: (2018)

Preparation of PLGA-Coated Porous Silica Nanofibers for Drug Release
por: Zhang, Meina, et al.
Publicado: (2022)

Identifiability analysis for models of the translation kinetics after mRNA transfection
por: Pieschner, Susanne, et al.
Publicado: (2022)

Mitochondrial mRNA localization is governed by translation kinetics and spatial transport
por: Arceo, Ximena G., et al.
Publicado: (2022)

Characterization of a Sandwich PLGA-Gallic Acid-PLGA Coating on Mg Alloy ZK60 for Bioresorbable Coronary Artery Stents
por: Lin, Li-Han, et al.
Publicado: (2020)

Gefitinib loaded PLGA and chitosan coated PLGA nanoparticles with magnified cytotoxicity against A549 lung cancer cell lines
por: Alshetaili, Abdullah S.
Publicado: (2021)

Release Retardation of Model Protein on Polyelectrolyte-Coated PLGA Nano- and Microparticles
por: Nugraha, Chandra, et al.
Publicado: (2014)

Functional Properties of Polyurethane Ureteral Stents with PLGA and Papaverine Hydrochloride Coating
por: Antonowicz, Magdalena, et al.
Publicado: (2021)

Hybrid Silica-Coated PLGA Nanoparticles for Enhanced Enzyme-Based Therapeutics
por: Gustafson, Kyle T., et al.
Publicado: (2022)

Harnessing Dendritic Cells for Poly (D,L-lactide-co-glycolide) Microspheres (PLGA MS)—Mediated Anti-tumor Therapy
por: Koerner, Julia, et al.
Publicado: (2019)

A Role for Dendritic Translation of CaMKIIα mRNA in Olfactory Plasticity
por: Néant-Fery, Marie, et al.
Publicado: (2012)

Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release
por: Mehanny, Mina, et al.
Publicado: (2020)

PreTIS: A Tool to Predict Non-canonical 5’ UTR Translational Initiation Sites in Human and Mouse
por: Reuter, Kerstin, et al.
Publicado: (2016)

Bioactive Ibuprofen-Loaded PLGA Coatings for Multifunctional Surface Modification of Medical Devices
por: Gherasim, Oana, et al.
Publicado: (2021)

Paclitaxel-Loaded PLGA Coating Stents in the Treatment of Benign Cicatrical Airway Stenosis
por: Qiu, Xiaojian, et al.
Publicado: (2022)

Association of Indocyanine Green with Chitosan Oleate Coated PLGA Nanoparticles for Photodynamic Therapy
por: Miele, Dalila, et al.
Publicado: (2022)

Microbiological Assessment of Titanium Plates Coated with PLGA, Chitosan, and/or Meropenem: An In Vitro Study
por: Al-Qubaisey, Mohammad, et al.
Publicado: (2022)

Characterization of Hyaluronic Acid-Coated PLGA Nanoparticles by Surface-Enhanced Raman Spectroscopy
por: La Verde, Giuseppe, et al.
Publicado: (2022)

Risperidone-Loaded PLGA–Lipid Particles with Improved Release Kinetics: Manufacturing and Detailed Characterization by Electron Microscopy and Nano-CT
por: Janich, Christopher, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_klglsg17trmaqlefo0hcavdnu0