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Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats

Botulinum neurotoxin A (BoNT) and brain-derived neurotrophic factor (BDNF) are known for their ability to influence synaptic inputs to neurons. Here, we tested if these drugs can modulate the deafferentation of motoneurons following nerve section/suture and, as a consequence, modify the outcome of p...

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Detalles Bibliográficos
Autores principales: Irintchev, Marcel, Guntinas-Lichius, Orlando, Irintchev, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145158/
https://www.ncbi.nlm.nih.gov/pubmed/30254669
http://dx.doi.org/10.1155/2018/7975013