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Effects of mutations in the effector domain of influenza A virus NS1 protein

OBJECTIVE: The multifunctional NS1 protein of influenza A virus has roles in antagonising cellular innate immune responses and promoting viral gene expression. To better understand the interplay between these functions, we tested the effects of NS1 effector domain mutations known to affect homo-dime...

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Detalles Bibliográficos
Autores principales: Pereira, Carina F., Wise, Helen M., Kurian, Dominic, Pinto, Rute M., Amorim, Maria J., Gill, Andrew C., Digard, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145200/
https://www.ncbi.nlm.nih.gov/pubmed/30227889
http://dx.doi.org/10.1186/s13104-018-3779-6