Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer

OBJECTIVE: Oesophageal cancer is the seventh most common cause of cancer-related death worldwide. Disease relapse is frequent and treatment options are limited. DESIGN: To identify new biomarker-defined therapeutic approaches for patients with oesophageal cancer, we integrated the genomic profiles o...

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Detalles Bibliográficos
Autores principales: Chong, Irene Yushing, Aronson, Lauren, Bryant, Hanna, Gulati, Aditi, Campbell, James, Elliott, Richard, Pettitt, Stephen, Wilkerson, Paul, Lambros, Maryou B, Reis-Filho, Jorge S, Ramessur, Anisha, Davidson, Michael, Chau, Ian, Cunningham, David, Ashworth, Alan, Lord, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Oesophagus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145286/
https://www.ncbi.nlm.nih.gov/pubmed/28830912
http://dx.doi.org/10.1136/gutjnl-2017-314408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145286/
https://www.ncbi.nlm.nih.gov/pubmed/28830912
http://dx.doi.org/10.1136/gutjnl-2017-314408

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