Cargando…
Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer
OBJECTIVE: Oesophageal cancer is the seventh most common cause of cancer-related death worldwide. Disease relapse is frequent and treatment options are limited. DESIGN: To identify new biomarker-defined therapeutic approaches for patients with oesophageal cancer, we integrated the genomic profiles o...
Autores principales: | Chong, Irene Yushing, Aronson, Lauren, Bryant, Hanna, Gulati, Aditi, Campbell, James, Elliott, Richard, Pettitt, Stephen, Wilkerson, Paul, Lambros, Maryou B, Reis-Filho, Jorge S, Ramessur, Anisha, Davidson, Michael, Chau, Ian, Cunningham, David, Ashworth, Alan, Lord, Christopher J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145286/ https://www.ncbi.nlm.nih.gov/pubmed/28830912 http://dx.doi.org/10.1136/gutjnl-2017-314408 |
Ejemplares similares
-
The prognostic value of TP53 mutations in oesophageal adenocarcinoma: a systematic review and meta-analysis
por: Fisher, Oliver M, et al.
Publicado: (2017) -
Local B cells and IgE production in the oesophageal mucosa in eosinophilic oesophagitis
por: Vicario, M, et al.
Publicado: (2010) -
IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis
por: Kaymak, Tanay, et al.
Publicado: (2023) -
The oesophageal string test: a novel, minimally invasive method measures mucosal inflammation in eosinophilic oesophagitis
por: Furuta, Glenn T, et al.
Publicado: (2013) -
Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia
por: Åsling, B, et al.
Publicado: (2009)