Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration

BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in children. Current problems in the clinic include metastasis, recurrence, and treatment-related sequelae that highlight the need for targeted therapies. Epigenetic perturbations are an established hallmark of human MB and ex...

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Detalles Bibliográficos
Autores principales: Callegari, Keri, Maegawa, Shinji, Bravo-Alegria, Javiera, Gopalakrishnan, Vidya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145331/
https://www.ncbi.nlm.nih.gov/pubmed/30227871
http://dx.doi.org/10.1186/s12964-018-0275-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145331/
https://www.ncbi.nlm.nih.gov/pubmed/30227871
http://dx.doi.org/10.1186/s12964-018-0275-5

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