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Pharmacological inhibition of LSD1 activity blocks REST-dependent medulloblastoma cell migration
BACKGROUND: Medulloblastoma (MB) is the most common malignant brain tumor in children. Current problems in the clinic include metastasis, recurrence, and treatment-related sequelae that highlight the need for targeted therapies. Epigenetic perturbations are an established hallmark of human MB and ex...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145331/ https://www.ncbi.nlm.nih.gov/pubmed/30227871 http://dx.doi.org/10.1186/s12964-018-0275-5 |