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The piRNA pathway responds to environmental signals to establish intergenerational adaptation to stress

BACKGROUND: piRNAs have a constitutive role in genome defence by silencing transposable elements in the germline. In the nematode Caenorhabditis elegans, piRNAs also induce epigenetic silencing of transgenes, which can be maintained for many generations in the absence of the piRNA pathway. The role...

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Detalles Bibliográficos
Autores principales: Belicard, Tony, Jareosettasin, Pree, Sarkies, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145337/
https://www.ncbi.nlm.nih.gov/pubmed/30227863
http://dx.doi.org/10.1186/s12915-018-0571-y