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Natural polymorphisms in the resistance associated sites of HCV-G1 NS5B domain and correlation with geographic origin of HCV isolates
BACKGROUND: We evaluated the frequency of naturally occurring resistance associated substitutions (RASs) and their characteristic of polymorphic or non-polymorphic amino acid change to direct acting antivirals (DAAs) in NS5b HCV subtypes 1a and 1b according to different geographic origin of isolates...
Autores principales: | Bagaglio, Sabrina, Uberti-Foppa, Caterina, Olgiati, Alessandro, Messina, Emanuela, Hasson, Hamid, Ferri, Camilla, Morsica, Giulia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145338/ https://www.ncbi.nlm.nih.gov/pubmed/30227876 http://dx.doi.org/10.1186/s12985-018-1054-z |
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