Autotaxin-β interaction with the cell surface via syndecan-4 impacts on cancer cell proliferation and metastasis

Autotaxin (ATX) promotes cancer cell metastasis through the production of lysophosphatidic acid (LPA). ATX binds to αvβ3 integrins controlling metastasis of breast cancer cells. We screened a series of cancer cell lines derived from diverse human and mouse solid tumors for the capacity of binding to...

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Detalles Bibliográficos
Autores principales: Leblanc, Raphael, Sahay, Debashish, Houssin, Audrey, Machuca-Gayet, Irma, Peyruchaud, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145688/
https://www.ncbi.nlm.nih.gov/pubmed/30237860
http://dx.doi.org/10.18632/oncotarget.26039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145688/
https://www.ncbi.nlm.nih.gov/pubmed/30237860
http://dx.doi.org/10.18632/oncotarget.26039

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