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Autotaxin-β interaction with the cell surface via syndecan-4 impacts on cancer cell proliferation and metastasis
Autotaxin (ATX) promotes cancer cell metastasis through the production of lysophosphatidic acid (LPA). ATX binds to αvβ3 integrins controlling metastasis of breast cancer cells. We screened a series of cancer cell lines derived from diverse human and mouse solid tumors for the capacity of binding to...
Autores principales: | Leblanc, Raphael, Sahay, Debashish, Houssin, Audrey, Machuca-Gayet, Irma, Peyruchaud, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145688/ https://www.ncbi.nlm.nih.gov/pubmed/30237860 http://dx.doi.org/10.18632/oncotarget.26039 |
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