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Comprehensive analysis identifying aberrant DNA methylation in rectal mucosa from ulcerative colitis patients with neoplasia

BACKGROUND: There are no biomarkers to facilitate the identification of patients with ulcerative colitis (UC) who are at high risk for developing colorectal cancer (CRC). In our current study, we used rectal tissues from UC patients to identify aberrant DNA methylations and evaluated whether they co...

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Detalles Bibliográficos
Autores principales: Toiyama, Yuji, Okugawa, Yoshinaga, Kondo, Satoru, Okita, Yoshiki, Araki, Toshimitsu, Kusunoki, Kurando, Uchino, Motoi, Ikeuchi, Hiroki, Hirota, Seiichi, Mitsui, Akira, Takehana, Kenji, Umezawa, Tsutomu, Kusunoki, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145694/
https://www.ncbi.nlm.nih.gov/pubmed/30237858
http://dx.doi.org/10.18632/oncotarget.26032