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miR-665 targets c-MYC and HDAC8 to inhibit murine neuroblastoma cell growth

Neuroblastoma is a common tumor of the peripheral nervous system in children. Highly aggressive MYC-driven neuroblastoma is defined by increased c-MYC and/or MYCN expression. This study employed a mouse neuroblastoma cell model to assess the role of miR-665 in tumorigenesis. We found that miR-665 su...

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Detalles Bibliográficos
Autor principal: Prashad, Nagindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145696/
https://www.ncbi.nlm.nih.gov/pubmed/30237861
http://dx.doi.org/10.18632/oncotarget.26046