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The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration

Melanoma is a highly immunogenic tumor with a good response to treatment with immune checkpoint inhibitors. Tumor-associated macrophages (TAMs) play an important immunosuppressive role in such tumors and have therefore been identified as possible future therapeutic targets in oncology. The aim of th...

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Detalles Bibliográficos
Autores principales: Dollt, Claudia, Michel, Julia, Kloss, Loreen, Melchers, Susanne, Schledzewski, Kai, Becker, Kathrin, Sauer, Andrea, Krewer, Andreas, Koll, Franziska, Schmieder, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145869/
https://www.ncbi.nlm.nih.gov/pubmed/30232321
http://dx.doi.org/10.1038/s41419-018-1011-1