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Identification and characterization of G-quadruplex formation within the EP0 promoter of pseudorabies virus

EP0 is an important early gene that modulates the life cycle of pseudorabies virus (PRV). A guanine-rich sequence overlapping with three Sp1 binding sites is located upstream of the transcription start site (TSS) in the EP0 promoter. Using native polyacrylamide gel electrophoresis (PAGE) and circula...

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Detalles Bibliográficos
Autores principales: kong, Jiang-Nan, Zhang, Chao, Zhu, Yan-Ce, Zhong, Kai, Wang, Jiang, Chu, Bei-Bei, Yang, Guo-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145870/
https://www.ncbi.nlm.nih.gov/pubmed/30232344
http://dx.doi.org/10.1038/s41598-018-32222-7