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N-Phenylquinazolin-2-amine Yhhu4952 as a novel promotor for oligodendrocyte differentiation and myelination

Oligodendrocytes are a type of glial cells that ensheath multiple neuronal axons and form myelin. Under pathological conditions, such as multiple sclerosis (MS), inflammatory damage to myelin and oligodendrocytes leads to demyelination. Although the demyelinated regions can partially resolve functio...

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Detalles Bibliográficos
Autores principales: Yu, Xueli, Cheng, Gang, Zhang, Lei, Zhang, Yu, Wang, Qing, Zhao, Mengxue, Zeng, Limin, Hu, Youhong, Feng, Linyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145871/
https://www.ncbi.nlm.nih.gov/pubmed/30232349
http://dx.doi.org/10.1038/s41598-018-32326-0