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Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance

Stem and progenitor cells of the submandibular salivary gland (SMG) give rise to, maintain, and regenerate the multiple lineages of mature epithelial cells including those belonging to the ductal, acinar, basal and myoepithelial subtypes. Here we have exploited single cell RNA-sequencing and in vivo...

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Detalles Bibliográficos
Autores principales: Song, Eun-Ah Christine, Min, Sangwon, Oyelakin, Akinsola, Smalley, Kirsten, Bard, Jonathan E., Liao, Lan, Xu, Jianming, Romano, Rose-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145895/
https://www.ncbi.nlm.nih.gov/pubmed/30232460
http://dx.doi.org/10.1038/s41598-018-32343-z