TGF-β1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA

Renal fibrosis is a histological manifestation that occurs in almost every type of chronic kidney disease. Histone variant H3.3 and its chaperone, histone cell cycle regulation defective homolog A (HIRA), serve as epigenetic marks that regulate transcriptional activity. In this study, we assessed th...

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Detalles Bibliográficos
Autores principales: Shindo, Toshihiro, Doi, Shigehiro, Nakashima, Ayumu, Sasaki, Kensuke, Arihiro, Koji, Masaki, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145928/
https://www.ncbi.nlm.nih.gov/pubmed/30232404
http://dx.doi.org/10.1038/s41598-018-32518-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145928/
https://www.ncbi.nlm.nih.gov/pubmed/30232404
http://dx.doi.org/10.1038/s41598-018-32518-8

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