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Asymmetric assembly of high-value α-functionalized organic acids using a biocatalytic chiral-group-resetting process

The preparation of α-functionalized organic acids can be greatly simplified by adopting a protocol involving the catalytic assembly of achiral building blocks. However, the enzymatic assembly of small amino acids and aldehydes to form numerous α-functionalized organic acids is highly desired and rem...

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Detalles Bibliográficos
Autores principales: Song, Wei, Wang, Jin-Hui, Wu, Jing, Liu, Jia, Chen, Xiu-Lai, Liu, Li-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145935/
https://www.ncbi.nlm.nih.gov/pubmed/30232330
http://dx.doi.org/10.1038/s41467-018-06241-x