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Identification of Distinct Unmutated Chronic Lymphocytic Leukemia Subsets in Mice Based on Their T Cell Dependency

Chronic lymphocytic leukemia (CLL) can be divided into prognostically distinct subsets with stereotyped or non-stereotyped, mutated or unmutated B cell receptors (BCRs). Individual subsets vary in antigen specificity and origin, but the impact of antigenic pressure on the CLL BCR repertoire remains...

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Detalles Bibliográficos
Autores principales: Pal Singh, Simar, de Bruijn, Marjolein J. W., de Almeida, Mariana P., Meijers, Ruud W. J., Nitschke, Lars, Langerak, Anton W., Pillai, Saravanan Y., Stadhouders, Ralph, Hendriks, Rudi W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146083/
https://www.ncbi.nlm.nih.gov/pubmed/30271400
http://dx.doi.org/10.3389/fimmu.2018.01996