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Distinct Treatment Outcomes of Antiparasitic Therapy in Trypanosoma cruzi-Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Phenotypes

Background: In contrast to adults, Trypanosoma cruzi-infected children have more broadly functional Trypanosoma cruzi-specific T cells, and the total T-cell compartment exhibits fewer signs of immune exhaustion. However, not much is known about the link between immunocompetence and the treatment eff...

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Detalles Bibliográficos
Autores principales: Albareda, María C., Natale, María A., De Rissio, Ana M., Fernandez, Marisa, Serjan, Alicia, Alvarez, María G., Cooley, Gretchen, Shen, Huifeng, Viotti, Rodolfo, Bua, Jacqueline, Castro Eiro, Melisa D., Nuñez, Myriam, Fichera, Laura E., Lococo, Bruno, Scollo, Karenina, Tarleton, Rick L., Laucella, Susana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146084/
https://www.ncbi.nlm.nih.gov/pubmed/30271399
http://dx.doi.org/10.3389/fimmu.2018.01958