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Distinct Treatment Outcomes of Antiparasitic Therapy in Trypanosoma cruzi-Infected Children Is Associated With Early Changes in Cytokines, Chemokines, and T-Cell Phenotypes
Background: In contrast to adults, Trypanosoma cruzi-infected children have more broadly functional Trypanosoma cruzi-specific T cells, and the total T-cell compartment exhibits fewer signs of immune exhaustion. However, not much is known about the link between immunocompetence and the treatment eff...
Autores principales: | Albareda, María C., Natale, María A., De Rissio, Ana M., Fernandez, Marisa, Serjan, Alicia, Alvarez, María G., Cooley, Gretchen, Shen, Huifeng, Viotti, Rodolfo, Bua, Jacqueline, Castro Eiro, Melisa D., Nuñez, Myriam, Fichera, Laura E., Lococo, Bruno, Scollo, Karenina, Tarleton, Rick L., Laucella, Susana A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146084/ https://www.ncbi.nlm.nih.gov/pubmed/30271399 http://dx.doi.org/10.3389/fimmu.2018.01958 |
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