G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis

The intestinal epithelial barrier is important to mucosal immunity, although how it is maintained after damage is unclear. Here, we show that G protein-coupled receptor 109A (GPR109A) supports barrier integrity and decreases mortality in a mouse cecum ligation and puncture (CLP) sepsis model. Data f...

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Detalles Bibliográficos
Autores principales: Chen, Guangxin, Huang, Bingxu, Fu, Shoupeng, Li, Bai, Ran, Xin, He, Dewei, Jiang, Liqiang, Li, Yuhang, Liu, Bingdong, Xie, Liwei, Liu, Juxiong, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146091/
https://www.ncbi.nlm.nih.gov/pubmed/30271409
http://dx.doi.org/10.3389/fimmu.2018.02079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146091/
https://www.ncbi.nlm.nih.gov/pubmed/30271409
http://dx.doi.org/10.3389/fimmu.2018.02079

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